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Third-party tested
Third-party tested
5-Amino-1MQ
Fat Loss
10mg
$50
Fat Loss Drug still being tested (Phase III)
RetatrutideResearch peptide · Ships within Canada
Also known as: LY3437943, Triple Agonist
Retatrutide is a newer triple agonist. That means it turns on three receptors (docking spots on cells) at once: GLP-1, GIP and glucagon. Eli Lilly is now testing it in Phase III human trials. So far, it has shown more weight loss than any other peptide. In Phase II trials, people lost 20–25%+ of their body weight (vs ~15% for Tirzepatide). The glucagon part makes the body burn more energy. This adds to the drop in appetite.
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$90
10mg
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Retatrutide is a newer triple agonist. That means it turns on three receptors (docking spots on cells) at once: GLP-1, GIP and glucagon. Eli Lilly is now testing it in Phase III human trials. So far, it has shown more weight loss than any other peptide. In Phase II trials, people lost 20–25%+ of their body weight (vs ~15% for Tirzepatide). The glucagon part makes the body burn more energy. This adds to the drop in appetite.
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In plain English
What does Retatrutide do?
Retatrutide is an investigational drug. That means it is still being tested in human trials and is not approved. It is studied for weight loss because it may lower hunger and help the body burn more energy.
What researchers study it for
- Weight loss. In earlier human trials, people lost more weight than in trials of similar drugs.
- Less hunger. It may strongly lower hunger and make the stomach empty more slowly.
- Burning more energy. It may raise how much energy the body burns, even at rest.
- Blood sugar. It may help the body control blood sugar better.
- Heart and metabolism. It may improve test results linked to heart health and metabolism.
How it works, in everyday words
Retatrutide flips three switches in the body at once, called GLP-1, GIP and glucagon receptors. The GLP-1 switch lowers hunger and slows how fast the stomach empties. The GIP switch helps the body handle blood sugar and fat. The glucagon switch makes the body burn more energy and break down fat.
Good to know
- It is injected under the skin once a week.
- The dose starts low and is raised slowly to limit stomach side effects.
- It is still in Phase III human trials and not yet approved. It is sold as a research chemical.
Buying Retatrutide in Canada
- Ships from inside Canada, so your order never crosses a border and never waits in customs.
- Orders placed Monday to Friday ship the same day by Canada Post Xpresspost, with tracking.
- Most orders arrive in 1 to 3 business days.
- Prices are in Canadian dollars. Shipping is free on orders over $199, or a $20 flat rate below that.
- Plain, private packaging with nothing on the outside that shows what is inside.
Every batch is tested by an outside lab, and the report is on our Lab Results page. Sold for laboratory research only. Full details: Shipping Policy.
Time in the Body
~6 days
Common Dose
Start at 2 mg/week, then raise by 2 mg every 4 weeks up to 8–12 mg/week
How It Is Given
Injection under the skin (belly, thigh or upper arm)
How Often
Once a week, as an injection under the skin
The Science Behind It
Retatrutide turns on three receptors at the same time. GLP-1 lowers appetite, slows how fast the stomach empties and helps control blood sugar. GIP helps the body respond better to insulin and supports how it uses fat. Glucagon makes the body burn more energy at rest and helps break down stored fat. Together, this lowers appetite PLUS speeds up metabolism. That mix is unique among incretin drugs (drugs that copy gut hormones).
What Research Suggests
- ✦Strongest weight-loss peptide now in testing (20–25%+ body weight loss)
- ✦Works on three receptors (GLP-1 + GIP + glucagon)
- ✦Makes the body burn more energy (glucagon effect)
- ✦Strongly lowers appetite
- ✦Better response to insulin and blood sugar control
- ✦Better heart and metabolism test results
- ✦Works for severe obesity and metabolic syndrome
Dosing Guide
Common doseStart at 2 mg/week, then raise by 2 mg every 4 weeks up to 8–12 mg/week
Range2–12 mg per week (human trials tested up to 12 mg)
How OftenOnce a week, as an injection under the skin
How it is givenInjection under the skin (belly, thigh or upper arm)
Notes
Comes in 10 mg, 20 mg and 30 mg vials. Always raise the dose slowly to limit stomach and gut side effects. 10 mg vial mixed with 2 mL bac water = 5 mg/mL (40 units = 2 mg, 80 units = 4 mg). Pair it with enough protein and strength training to keep muscle.
Where Research Stands
In Phase III human trials. Not yet FDA-approved. So far, it has the best weight-loss results of any incretin (gut hormone) drug trial.
How to Store It
Powder: keep in the fridge. After mixing: keep in the fridge and use within 30 days.
Legal Status
Drug still being tested (Phase III). Not yet approved. Sold as a research chemical.
Dose Calculator
Retatrutide's vial size is already filled in. Enter how much water you add and the dose you want. It shows exactly how many units to draw.
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Results
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Quick Reference
1 mg= 1,000 mcg
1 mL= 100 units (on a 100u syringe)
1 mL= 1 cc
Usual mixing amount1–3 mL bacteriostatic water per vial
How long will this vial last?
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Research use only. This calculator only does the math for trained lab staff. It does not suggest a dose, an amount to inject, a treatment, or any use in people. Always follow your approved lab plan, the product paperwork and the rules where you work.
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For laboratory research purposes only. Not for human use. Not medical advice.