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KPVResearch peptide · Ships within Canada
Also known as: Lys-Pro-Val, α-MSH (11-13)
KPV is a very small peptide made of lysine, proline and valine. It is the tail end of alpha-MSH, a hormone that also controls skin color. KPV keeps alpha-MSH's strong power to calm inflammation (swelling) and balance the immune system. But it does not darken the skin. KPV is best known for calming gut inflammation, for skin problems, and for the link between the gut and skin.
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$55
10mg
Free Xpresspost shipping on orders over $199
KPV is a very small peptide made of lysine, proline and valine. It is the tail end of alpha-MSH, a hormone that also controls skin color. KPV keeps alpha-MSH's strong power to calm inflammation (swelling) and balance the immune system. But it does not darken the skin. KPV is best known for calming gut inflammation, for skin problems, and for the link between the gut and skin.
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In plain English
What does KPV do?
KPV is a tiny piece of a hormone called alpha-MSH, just three building blocks long. It is studied for calming inflammation, especially in the gut and skin.
What researchers study it for
- Gut inflammation. It is studied for calming an inflamed gut, including bowel diseases like colitis.
- Gut lining repair. Research suggests it may help repair the gut's protective lining.
- Skin and acne. It may help calm acne and red, irritated skin.
- Wound healing. Researchers look at how it may support wound healing.
- Fighting germs. It has also shown some germ-fighting activity in research.
How it works, in everyday words
KPV keeps the calming power of alpha-MSH, but it does not change skin color. It gets inside cells and turns down the alarm signals that immune cells use to start inflammation. It seems to work especially well on the cells that line the gut.
Good to know
- In research it is injected under the skin once a day. Research describes it as generally well tolerated.
- It has been studied for decades. It is sold for research only and is not approved to treat people.
Buying KPV in Canada
- Ships from inside Canada, so your order never crosses a border and never waits in customs.
- Orders placed Monday to Friday ship the same day by Canada Post Xpresspost, with tracking.
- Most orders arrive in 1 to 3 business days.
- Prices are in Canadian dollars. Shipping is free on orders over $199, or a $20 flat rate below that.
- Plain, private packaging with nothing on the outside that shows what is inside.
Every batch is tested by an outside lab, and the report is on our Lab Results page. Sold for laboratory research only. Full details: Shipping Policy.
Time in the Body
~15–30 minutes
Common Dose
200–500 mcg per day
How It Is Given
Injection under the skin
How Often
Once a day
The Science Behind It
KPV gets inside cells and acts on melanocortin receptors (MC1R, MC3R). Receptors are docking spots that pass on signals. This turns down NF-kB, a signal that drives inflammation. It also lowers cytokines (TNF-α, IL-6, IL-8), which are messages that cause swelling. It calms inflammation right where immune cells first switch on. It works especially well on the cells lining the gut. That is why it is often used for IBD, leaky gut and other bowel inflammation problems.
What Research Suggests
- ✦Strong effects that calm inflammation (swelling)
- ✦Repair of the gut lining and support for IBD/colitis
- ✦Less acne and skin inflammation
- ✦Improves the gut-skin axis
- ✦Wound healing support
- ✦Acts against germs (anti-microbial)
- ✦Generally very well-tolerated
Dosing Guide
Common dose200–500 mcg per day
Range200–1000 mcg per day
How OftenOnce a day
How it is givenInjection under the skin
Notes
10 mg vial — mix with 2 mL bac water → 5 mg/mL: 10 units (0.1 mL) = 500 mcg. A cycle lasts 4–8 weeks.
Where Research Stands
It has been studied for several decades. Research covers inflammation, IBD and skin (dermatology). It is not yet approved as a medicine.
How to Store It
Powder: keep in the fridge. After mixing: keep in the fridge and use within 30 days.
Legal Status
Sold for research only. Not approved to treat people.
Often Paired With
Dose Calculator
KPV's vial size is already filled in. Enter how much water you add and the dose you want. You will see exactly how many units to draw.
The mg number printed on the vial label
How much bacteriostatic water you mix in
Micrograms (mcg) you want each time
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Results
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Amount to Inject
—mL
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Quick Reference
1 mg= 1,000 mcg
1 mL= 100 units (on a 100u syringe)
1 mL= 1 cc
Usual mixing amount1–3 mL bacteriostatic water per vial
How long will this vial last?
Pick the vial size, enter how much you use each time, and how many times a week. We will estimate how long the vial lasts.
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Research use only. This calculator only does the math for trained lab staff. It does not suggest a dose, an amount to inject, a treatment, or any use in people. Always follow your approved lab plan, the product paperwork and the rules where you work.
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Zenova Peptides
For laboratory research purposes only. Not for human use. Not medical advice.